Bartolini, Manuela: search on Z-Library

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1

Solid lipid microparticles for oral delivery of catalase: focus on the protein structural integrity and gastric protection

Bertoni, Serena, Tedesco, Daniele, Bartolini, Manuela, Prata, Cecilia, Passerini, Nadia, Albertini, Beatrice

Journal:

Molecular Pharmaceutics

Year:

2020

File:

PDF, 1.33 MB

2020

2

Glycosaminoglycans Metabolism

Viola, Manuela, Douglas, Timothy E. L., Alaniz, Laura, Bartolini, Barbara

Journal:

Biochemistry Research International

Year:

2012

Language:

english

File:

PDF, 42 KB

english, 2012

3

A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases

Staderini, Matteo, Aulić, Suzana, Bartolini, Manuela, Tran, Hoang Ngoc Ai, González-Ruiz, Víctor, Pérez, Daniel I., Cabezas, Nieves, Martínez, Ana, Martín, M. Antonia, Andrisano, Vincenza, Legname, Gi

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

4

Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation

Simoni, Elena, Bartolini, Manuela, Abu, Izuddin F, Blockley, Alix, Gotti, Cecilia, Bottegoni, Giovanni, Caporaso, Roberta, Bergamini, Christian, Andrisano, Vincenza, Cavalli, Andrea, Mellor, Ian R, Mi

Journal:

Future Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.36 MB

english, 2017

5

Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018

De Simone, Angela, Naldi, Marina, Bartolini, Manuela, Davani, Lara, Andrisano, Vincenza

Journal:

Chromatographia

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

6

Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein–huprine hybrids

Pérez-Areales, Francisco Javier, Betari, Nibal, Viayna, Antonio, Pont, Caterina, Espargaró, Alba, Bartolini, Manuela, De Simone, Angela, Rinaldi Alvarenga, José Fernando, Pérez, Belén, Sabate, Raimon,

Journal:

Future Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

7

Rational Approach To Discover Multipotent Anti-Alzheimer Drugs

Rosini, Michela, Andrisano, Vincenza, Bartolini, Manuela, Bolognesi, Maria L., Hrelia, Patrizia, Minarini, Anna, Tarozzi, Andrea, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 75 KB

english, 2005

8

Inhibition of Acetylcholinesterase, β-Amyloid Aggregation, and NMDA Receptors in Alzheimer’s Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush

Simoni, Elena, Bartolini, Manuela, Cavalli, Andrea, Ceccarini, Luisa, Pascu, Nicoleta, McClymont, David W., Rosini, Michela, Tarozzi, Andrea, Bolognesi, Maria L., Minarini, Anna

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

9

Sette racconti cattolici

Gieri, Manuela, Bartolini, Elio

Journal:

World Literature Today

Year:

1993

Language:

english

File:

PDF, 371 KB

english, 1993

10

Chemical and Pharmacological Studies on Enantiomerically Pure p-Methoxytacripyrines, Promising Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease

Dr. Manuela Bartolini, Dr. Marco Pistolozzi, Prof. Vincenza Andrisano, Dr. Javier Egea, Prof. Manuela G. López, Prof. Isabel Iriepa, Ignacio Moraleda, Prof. Enrique Gálvez, Prof. José Marco-Contelles,

Journal:

Year:

2011

Language:

english

File:

PDF, 932 KB

english, 2011

11

New electrophoretic and chromatographic techniques for analysis of heparin and heparan sulfate

Manuela Viola, Davide Vigetti, Evgenia Karousou, Barbara Bartolini, Anna Genasetti, Manuela Rizzi, Moira Clerici, Francesco Pallotti, Giancarlo De Luca, Alberto Passi

Journal:

ELECTROPHORESIS

Year:

2008

Language:

english

File:

PDF, 313 KB

english, 2008

12

The role of Li+, Na+, and K+ in the ligand binding inside the human acetylcholinesterase gorge

Gabriele Petraglio, Manuela Bartolini, Davide Branduardi, Vincenza Andrisano, Maurizio Recanatini, Francesco Luigi Gervasio, Andrea Cavalli, Michele Parrinello

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

13

Heterocyclic inhibitors of AChE acylation and peripheral sites

Maria Laura Bolognesi, Vincenza Andrisano, Manuela Bartolini, Andrea Cavalli, Anna Minarini, Maurizio Recanatini, Michela Rosini, Vincenzo Tumiatti, Carlo Melchiorre

Journal:

Year:

2005

Language:

english

File:

PDF, 411 KB

english, 2005

14

Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor

Aráoz, Rómulo, Bouet, Monika, Bartolini, Manuela, Coquelle, Nicolas, Colletier, Jacques-Philippe, Servent, Denis, Molgo, Jordi, Jean, Ludovic, Renard, Pierre-Yves

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 160 KB

english, 2015

15

Combination of human acetylcholinesterase and serum albumin sensing surfaces as highly informative analytical tool for inhibitor screening

Fabini, Edoardo, Tramarin, Anna, Bartolini, Manuela

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 954 KB

english, 2018

16

New insights into the altered binding capacity of pharmaceutical-grade human serum albumin: site-specific binding studies by induced circular dichroism spectroscopy

Tramarin, Anna, Tedesco, Daniele, Naldi, Marina, Baldassarre, Maurizio, Bertucci, Carlo, Bartolini, Manuela

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 832 KB

english, 2019

17

Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers

Stefano Rizzo, Alessandra Bisi, Manuela Bartolini, Francesca Mancini, Federica Belluti, Silvia Gobbi, Vincenza Andrisano, Angela Rampa

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

18

The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease?

Rampa, Angela, Bartolini, Manuela, Bisi, Alessandra, Belluti, Federica, Gobbi, Silvia, Andrisano, Vincenza, Ligresti, Alessia, Di Marzo, Vincenzo

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 237 KB

english, 2012

19

Strategies for the Inhibition of Protein Aggregation in Human Diseases

Manuela Bartolini, Vincenza Andrisano

Journal:

Year:

2010

Language:

english

File:

PDF, 932 KB

english, 2010

20

Structure–Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine

Stefano Rizzo, Andrea Cavalli, Luisa Ceccarini, Manuela Bartolini, Federica Belluti, Alessandra Bisi, Vincenza Andrisano, Maurizio Recanatini, Angela Rampa

Journal:

Year:

2009

Language:

english

File:

PDF, 679 KB

english, 2009

21

Cholinesterase Inhibitors: Xanthostigmine Derivatives Blocking the Acetylcholinesterase-Induced β-Amyloid Aggregation

Belluti, Federica, Rampa, Angela, Piazzi, Lorna, Bisi, Alessandra, Gobbi, Silvia, Bartolini, Manuela, Andrisano, Vincenza, Cavalli, Andrea, Recanatini, Maurizio, Valenti, Piero

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 303 KB

english, 2005

22

Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer′s Disease

Prati, Federica, Bergamini, Christian, Fato, Romana, Soukup, Ondrej, Korabecny, Jan, Andrisano, Vincenza, Bartolini, Manuela, Bolognesi, Maria Laura

Journal:

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

23

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

Abdelouahid Samadi, Cristóbal de los Ríos, Irene Bolea, Mourad Chioua, Isabel Iriepa, Ignacio Moraleda, Manuela Bartolini, Vincenza Andrisano, Enrique Gálvez, Carolina Valderas, Mercedes Unzeta, José

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

24

Structure−Activity Relationships of Methoctramine-Related Polyamines as Muscular Nicotinic Receptor Noncompetitive Antagonists. 3.1 Effect of Inserting the Tetraamine Backbone into a Macrocyclic Structure

Angeli, Piero, Antonello, Alessandra, Rosini, Michela, Tumiatti, Vincenzo, Hucho, Ferdinand, Bolognesi, Maria L., Bixel, M. Gabriele, Marucci, Gabriella, Bartolini, Manuela, Krauss, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

25

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer

Tumiatti, Vincenzo, Milelli, Andrea, Minarini, Anna, Rosini, Michela, Bolognesi, Maria Laura, Micco, Marialuisa, Andrisano, Vincenza, Bartolini, Manuela, Mancini, Francesca, Recanatini, Maurizio, Cava

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

26

The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti-Alzheimer Multitarget Profile of Dimebon

Rosini, Michela, Simoni, Elena, Bartolini, Manuela, Soriano, Elena, Marco-Contelles, José, Andrisano, Vincenza, Monti, Barbara, Windisch, Manfred, Hutter-Paier, Birgit, McClymont, David W., Mellor, Ia

Journal:

Year:

2013

Language:

english

File:

PDF, 640 KB

english, 2013

27

Insight Into the Kinetic of Amyloid β (1–42) Peptide Self-Aggregation: Elucidation of Inhibitors’ Mechanism of Action

Manuela Bartolini, Carlo Bertucci, Maria Laura Bolognesi, Andrea Cavalli, Carlo Melchiorre, Vincenza Andrisano

Journal:

Year:

2007

Language:

english

File:

PDF, 509 KB

english, 2007

28

P1-339 Memoquin: a new therapeutic poly-agent for Alzheimer's disease

Andrea Cavalli, Maria Laura Bolognesi, Manuela Bartolini, Vincenza Andrisano, Carlo Melchiorre, Maurizio Recanatani, Elisa Margotti, Simona Capsoni, Antonino Cattaneo

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

29

Fibromodulin Interactions with Type I and II Collagens

Viola, Manuela, Bartolini, Barbara, Sonaggere, Myriam, Giudici, Camilla, Tenni, Ruggero, Tira, M. Enrica

Journal:

Connective Tissue Research

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

30

Fluorescence biosensing micropatterned surfaces based on immobilized human acetylcholinesterase

Manuela Bartolini, Marina Naldi, Dan V. Nicolau…

Journal:

Analytical and Bioanalytical Chemistry

Year:

2013

Language:

english

File:

PDF, 421 KB

english, 2013

31

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 2. Role of the Substituents on the Phenyl Ring and Nitrogen Atoms of Caproctamine

Tumiatti, Vincenzo, Rosini, Michela, Bartolini, Manuela, Cavalli, Andrea, Marucci, Gabriella, Andrisano, Vincenza, Angeli, Piero, Banzi, Rita, Minarini, Anna, Recanatini, Maurizio, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 258 KB

english, 2003

32

Analysis of Glycosaminoglycans by Electrophoretic Approach

Karousou, Evgenia, Viola, Manuela, Vigetti, Davide, Genasetti, Anna, Rizzi, Manuela, Clerici, Moira, Bartolini, Barbara, Luca, Giancarlo, Passi, Alberto

Journal:

Current Pharmaceutical Analysis

Year:

2008

Language:

english

File:

PDF, 310 KB

english, 2008

33

Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives

Montanari, Serena, Bartolini, Manuela, Neviani, Paolo, Belluti, Federica, Gobbi, Silvia, Pruccoli, Letizia, Tarozzi, Andrea, Falchi, Federico, Andrisano, Vincenza, Miszta, Przemysław, Cavalli, Andrea,

Journal:

Year:

2016

Language:

english

File:

PDF, 7.64 MB

english, 2016

34

Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer’s Disease: A Rational Approach

Simoni, Elena, Serafini, Melania M., Caporaso, Roberta, Marchetti, Chiara, Racchi, Marco, Minarini, Anna, Bartolini, Manuela, Lanni, Cristina, Rosini, Michela

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

35

Chalcone-based carbamates for Alzheimer’s disease treatment

Rampa, Angela, Montanari, Serena, Pruccoli, Letizia, Bartolini, Manuela, Falchi, Federico, Feoli, Alessandra, Cavalli, Andrea, Belluti, Federica, Gobbi, Silvia, Tarozzi, Andrea, Bisi, Alessandra

Journal:

Future Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

36

A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017

Andrisano, Vincenza, Naldi, Marina, De Simone, Angela, Bartolini, Manuela

Journal:

Expert Opinion on Therapeutic Patents

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

37

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors

Pérez-Areales, F. Javier, Turcu, Andreea L., Barniol-Xicota, Marta, Pont, Caterina, Pivetta, Deborah, Espargaró, Alba, Bartolini, Manuela, De Simone, Angela, Andrisano, Vincenza, Pérez, Belén, Sabate,

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 678 KB

english, 2019

38

ChemInform Abstract: Exploiting the Lipoic Acid Structure in the Search for Novel Multitarget Ligands Against Alzheimer′s Disease.

Michela Rosini, Elena Simoni, Manuela Bartolini, Andrea Tarozzi, Riccardo Matera, Andrea Milelli, Patrizia Hrelia, Vincenza Andrisano, Maria Laura Bolognesi, Carlo Melchiorre

Journal:

Year:

2012

File:

PDF, 22 KB

2012

39

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer’s disease

Michela Rosini, Elena Simoni, Manuela Bartolini, Andrea Tarozzi, Riccardo Matera, Andrea Milelli, Patrizia Hrelia, Vincenza Andrisano, Maria Laura Bolognesi, Carlo Melchiorre

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

40

The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90

Manuela Bartolini, Irving W. Wainer, Carlo Bertucci, Vincenza Andrisano

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2013

Language:

english

File:

PDF, 308 KB

english, 2013

41

Hexahydrochromeno[4,3- b ]pyrrole Derivatives as Acetylcholinesterase Inhibitors

Bolognesi, Maria L., Andrisano, Vincenza, Bartolini, Manuela, Minarini, Anna, Rosini, Michela, Tumiatti, Vincenzo, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

42

Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

Nepovimova, Eugenie, Uliassi, Elisa, Korabecny, Jan, Peña-Altamira, Luis Emiliano, Samez, Sarah, Pesaresi, Alessandro, Garcia, Gregory E., Bartolini, Manuela, Andrisano, Vincenza, Bergamini, Christian

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.86 MB

english, 2014

43

Extensive SAR and Computational Studies of 3-{4-[(Benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2 H -2-chromenone (AP2238) Derivatives

Piazzi, Lorna, Cavalli, Andrea, Belluti, Federica, Bisi, Alessandra, Gobbi, Silvia, Rizzo, Stefano, Bartolini, Manuela, Andrisano, Vincenza, Recanatini, Maurizio, Rampa, Angela

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

44

From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer's disease

Tarozzi, Andrea, Bartolini, Manuela, Piazzi, Lorna, Valgimigli, Luca, Amorati, Riccardo, Bolondi, Cecilia, Djemil, Alice, Mancini, Francesca, Andrisano, Vincenza, Rampa, Angela

Journal:

Pharmacology Research & Perspectives

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

45

Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines

Bartolini, Manuela, Marco-Contelles, José

Journal:

The Chemical Record

Year:

2018

Language:

english

File:

PDF, 3.53 MB

english, 2018

46

No G-Quadruplex Structures in the DNA of Parvovirus B19: Experimental Evidence versus Bioinformatic Predictions

Bua, Gloria, Tedesco, Daniele, Conti, Ilaria, Reggiani, Alessandro, Bartolini, Manuela, Gallinella, Giorgio

Journal:

Year:

2020

File:

PDF, 2.22 MB

2020

47

A Small Molecule Targeting the Multifactorial Nature of Alzheimer's Disease

Andrea Cavalli, Maria Laura Bolognesi, Simona Capsoni, Vincenza Andrisano, Manuela Bartolini, Elisa Margotti, Antonino Cattaneo, Maurizio Recanatini, Carlo Melchiorre

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 238 KB

english, 2007

48

A Small Molecule Targeting the Multifactorial Nature of Alzheimer's Disease

Andrea Cavalli, Maria Laura Bolognesi, Simona Capsoni, Vincenza Andrisano, Manuela Bartolini, Elisa Margotti, Antonino Cattaneo, Maurizio Recanatini, Carlo Melchiorre

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

49

Characterization of reversible and pseudo-irreversible acetylcholinesterase inhibitors by means of an immobilized enzyme reactor

Manuela Bartolini, Vanni Cavrini, Vincenza Andrisano

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 621 KB

english, 2007

50

Fatty acid amide hydrolase (FAAH), acethylcholinesterase (AChE) and butyrylcholinesterase (BuChE): networked targets for the development of carbamates as potential anti Alzheimer’s Disease agents

Montanari, Serena, Scalvini, Laura, Bartolini, Manuela, Belluti, Federica, Gobbi, Silvia, Andrisano, Vincenza, Ligresti, Alessia, Di Marzo, Vincenzo, Rivara, Silvia, Mor, Marco, Bisi, Alessandra, Ramp

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

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